官网链接
折扣/货期| 货号：9004311-1 mg | 规格：1 mg | 目录价：￥3878 |
| 货号：9004311-500 µg | 规格：500 µg | 目录价：￥2156 |
产品详情
产品名称:
BAY 57-1293-d4
别名:
Pritelivir-d4
产品描述:
BAY 57-1293-d4 is intended for use as an internal standard for the quantification of BAY 57-1293 (Item No. 22129) by GC- or LC-MS. BAY 57-1293 is an orally bioavailable helicase-primase inhibitor.{39314} It inhibits the ATPase activity of herpes simplex virus (HSV) helicase-primase (IC50 = 30 nM). It inhibits HSV replication in Vero cells (IC50 = 20 nM for both HSV-1 and HSV-2) and is also active against porcine and bovine HSV strains (IC50s = 5 and 0.12 μM, respectively). In vivo, oral administration of BAY 57-1293 is effective against HSV-1 and HSV-2 in a lethal challenge model (ED50 = 0.5 mg/kg in mice and rats) and in a zosteriform spread model, at a dose of 15 mg/kg, in mice and Lewis rats.{39314,39315} It is also effective in a guinea pig model of genital herpes and a mouse model of ocular herpes. BAY 57-1293 reduces levels of amyloid-beta (Aβ) and phosphorylated Tau in HSV-1 infected Vero cells.{39316}
保存温度:
-20
运输温度:
-20
预期分子量:
406.5
产品形式:
A solid
有效期:
730
纯度:
≥99% deuterated forms (d1-d4)
分子式:
C18H14D4N4O3S2
您可能感兴趣的产品
Human Ovary (Normal) tissue slides
货号：GTX03349
Trident High-Efficiency Exosome Precipitation Reagent
货号：GTX00835
SARS-CoV-2 (COVID-19) Spike (Omicron BA.4 / BA.5) FFPE 293T Cell Pellet Block
货号：GTX437396
Alzheimer brain : hippocampus tissue slides
货号：GTX24583
Human Brain: Hippocampus (Normal) tissue slides
货号：GTX24305
Human Brain: Hippocampus (Parkinson's Disease) tissue slides
货号：GTX22222
Mouse Tissue Array III - Normal Tissues
货号：GTX03659
Tween 20
货号：GTX03634
促销活动
