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anti-ACE2 (human), mAb (AC18F) (Biotin)
品牌：Adipogen
货号：AG-20A-0032B-C050 规格：50 ug 目录价：￥3120
产品详情
产品名称:
anti-ACE2 (human), mAb (AC18F) (Biotin)
别名:
SARS Receptor; Angiotensin-converting Enzyme 2; ACEH; Metalloprotease MPROT15; SARS-CoV-2 Receptor
产品描述:
Angiotensin-converting enzyme2 (ACE2) is an ectoenzyme (carboxypeptidase) with an extracellular catalytic domain that predominantly localizes at the plasma membrane and is thereby able to hydrolyze circulating peptides. ACE2 has approximately 42% sequence identity with ACE, and its cytoplasmic and transmembrane domains show 48% homology to the protein collectrin that plays a critical role in the amino acid absorption of the kidney. ACE2 converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. ACE2 is involved in the regulation of systemic blood pressure and has direct effects on cardiac functions. It is expressed predominantly in endothelial cells of the lung, gut, heart and kidney. ACE2 together with the protease TMPRSS2 acts as a functional receptor for SARS coronavirus as well as for the new highly pathogenic coronavirus, 2019-nCoV/SARS-CoV-2, which is cause for pneumonia COVID-19.
实验应用:
ELISA, FACS, WB
靶标/特异性:
Recognizes human ACE2. Does not detect recombinant human ACE2 that has a tag at the C-terminus of the protein.
同种型:
Mouse IgG1kappa
免疫原:
Recombinant human ACE2.
克隆号:
AC18F
偶联:
Biotin
产品浓度:
1mg/ml
保存温度:
-20°C
运输温度:
BLUE ICE
产品形式:
liquid
存储溶液:
Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives.
有效期:
Stable for at least 1 year after receipt when stored at -20°C.
产地:
瑞士
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