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折扣/货期| 货号：AG-CMA-1001-C200 | 规格：200 ug | 目录价：￥2760 |
产品详情
产品名称:
Ageladine A . TFA
别名:
(4-(4,5-Dibromo-1H-pyrrol-2-yl)-1H-imidazo[4,5-c]-pyridin-2-amine) . TFA
产品描述:
Non-toxic, pH-sensitive fluorescent dye (blue-green range) for live imaging of pH alteration in acidic organelles, vesicles, cells, tissue and even small whole animals over several days without side effects [2,4,5,7-9]. Stronger fluorescent intensity under acidic conditions and barely detectable in alkaline solutions (wide range from pH 4 to pH 8) [2]. Highly cell/membrane permeable. Trapped within the cells and acidic organelles through hydrophobic interactions with the inner side of the membranes [2]. Barely metabolized and long-term stable, thus slow photobleaching [9]. Angiogenesis inhibitor [1,3,6]. Inhibitor of matrix metalloproteinases MMP-1,-2,-8,-9,-12,-13 [1, 3-6]. TYK2, DYRK2,Dyrk1A, YSK4 and RPS6KA1/2 inhibitor [3,5,6].
宿主来源:
Synthetic. Originally isolated from Agelas nakamurai.
保存温度:
-20°C
运输温度:
Ambient
预期分子量:
357.0 . 114.0
产品形式:
solid
有效期:
Stable for at least 1 year after receipt when stored at +4°C. Stock solutions are stable for at least 3 months when stored at -20°C.
产地:
瑞士
纯度:
>98% (NMR)
CAS号:
950766-21-9 | 643020-13-7 (free base)
分子式:
C10H7Br2N5 . C2HF3O2
溶解度:
Soluble in DMSO or methanol.
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