货号:34469-1 mg | 规格:1 mg | 目录价:¥5950 |
货号:34469-5 mg | 规格:5 mg | 目录价:¥26684 |
产品详情
产品名称:
Ac-FLTD-CMK (trifluoroacetate salt)
别名:
Ac-Phe-Leu-Thr-Asp-CMK
产品描述:
Ac-FLTD-CMK is an inhibitor of caspase-1, -4, -5, and -11.{61775} It inhibits caspase-1, -4, and -5 (IC50s = 0.0467, 1.49, and 0.329, respectively, for the recombinant human enzymes) and cleavage of gasdermin D (GSDMD), an effector involved in pyroptosis and NETosis, by mouse caspase-11 when used at a concentration of 10 µM. Ac-FLTD-CMK (10 µM) inhibits LPS- and ATP- or LPS- and nigericin-induced pyroptosis and IL-1β release in mouse bone marrow-derived macrophages (BMDMs).
保存温度:
-20
运输温度:
-20
预期分子量:
569
产品形式:
A solid
有效期:
1460
纯度:
≥95%
分子式:
C26H37ClN4O8 • XCF3COOH
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