ACE2 (human) Monoclonal Antibody - Biotinylated (Clone AC18F)-单抗-ELISA_抗体_蛋白_核苷酸

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ACE2 (human) Monoclonal Antibody - Biotinylated (Clone AC18F)

品牌：Cayman

官网链接

说明书

折扣/货期

货号：30583

规格：50 µg

目录价：￥5491

产品详情

产品名称:

ACE2 (human) Monoclonal Antibody - Biotinylated (Clone AC18F)

别名:

ACEH|ACE-related Carboxypeptidase|Angiotensin-converting Enzyme 2|Angiotensin-converting Enzyme Homolog|Metalloprotease MPROT15

产品描述:

Angiotensin-converting enzyme 2 (ACE2) is a carboxypeptidase and homolog of ACE1 that is encoded by ACE2 in humans.{53456,53457} It is a type I transmembrane protein composed of a cytoplasmic tail and an extracellular domain containing an HEMGH motif, characteristic of zinc-metallopeptidases, which exhibits carboxymonopeptidase activity.{53456} ACE2 is expressed in vascular endothelial cells where it catalyzes the conversion of angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to the vasodilatory peptide angiotensin 1-7 to regulate systemic blood pressure.{53456,53457} It is also expressed in the epithelial cells of the kidney, heart, lung, small intestine, and liver and has roles in fluid homeostasis, cardiac contractility, and amino acid absorption, as well as the prevention of pulmonary fibrosis and hypertension. ACE2 also acts as a functional receptor for severe acute respiratory syndrome coronavirus (SARS-CoV) and SARS-CoV-2 to facilitate viral entry into host cells.{49542,53458} Cayman's ACE2 (human) Monoclonal Antibody-Biotinylated (Clone AC18F) can be used for ELISA, flow cytometry (FC), and Western blot (WB) applications.

宿主来源:

Mouse

实验应用:

ELISA, FC, and WB

同种型:

IgG1κ

免疫原:

Recombinant human ACE2

克隆号:

AC18F

保存温度:

-20