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Ac2-26 (human) (ammonium salt)
货号:34429-1 mg 规格:1 mg 目录价:¥1190
货号:34429-10 mg 规格:10 mg 目录价:¥8260
货号:34429-25 mg 规格:25 mg 目录价:¥17682
货号:34429-5 mg 规格:5 mg 目录价:¥4438
产品详情
产品名称:
Ac2-26 (human) (ammonium salt)
别名:
Ac-AMVSEFLKQAWFIENEEQEYVQTVK-OH|Ac-ANX-A12-26|N-Acetyl-AMVSEFLKQAWFIENEEQEYVQTVK
产品描述:
Ac2-26 is an annexin A1-mimetic peptide that corresponds to amino acids 2-26 of the N-terminus in annexin A1.{57827} It binds to HEK293 cells expressing human formyl peptide receptor 1 (FPR1) or FPR2, also known as FPR-like 1 (FPRL1; EC50s = 1.4 and 1.8 µM, respectively, in a radioligand binding assay), as well as inhibits polymorphonuclear leukocyte (PMN) rolling over TNF-α-stimulated human umbilical vein endothelial cells (HUVECs) when used at concentrations of 10 and 30 µM. Ac2-26 (10 and 100 µg/ml) inhibits LPS-induced production of prostaglandin E2 (PGE2; Item No. 14010) and nitric oxide (NO) in rat microglial cells.{57828} It decreases pulmonary edema in a rat model of ventilator-induced ischemia-reperfusion injury when administered at doses of 0.5 and 1 mg/kg.{57829}
保存温度:
-20
运输温度:
-20
预期分子量:
3107.5
产品形式:
A solid
有效期:
1460
纯度:
≥90%
分子式:
C141H210N32O44S • NH4
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