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折扣/货期| 货号：316350-100 µg | 规格：100 µg | 目录价：￥8218 |
| 货号：316350-25 µg | 规格：25 µg | 目录价：￥2310 |
| 货号：316350-50 µg | 规格：50 µg | 目录价：￥4354 |
产品详情
产品名称:
8-iso Prostaglandin F2α-d4
别名:
15-F2t-Isoprostane-d4|8-epi PGF2α-d4|8-Isoprostane-d4|iPF2α-III-d4
产品描述:
8-iso PGF2α-d4 is intended for use as an internal standard for the quantification of 8-iso PGF2α by GC- or LC-mass spectrometry. 8-iso Prostaglandin F2α (8-iso PGF2α) is an isoprostane produced by the non-enzymatic peroxidation of arachidonic acid in membrane phospholipids.{320,371,855} It circulates in human plasma in two distinct forms - esterified in LDL phospholipids and as the free acid. The ratio of these two forms is approximately 2:1, with a total plasma 8-iso PGF2α level of about 150 pg/ml in normal volunteers. In normal human urine, 8-iso PGF2α levels are about 180-200 pg/mg of creatinine.{320,371} 8-iso PGF2α is a weak TP receptor agonist in vascular smooth muscle.{6640} Conversely, 8-iso PGF2α inhibits platelet aggregation induced by U-46619 (10−6 M) and I-BOP (3 x 10−7 M) with IC50 values of 1.6 x 10−6 M and 1.8 x 10−6 M, respectively.{855}
保存温度:
-20
运输温度:
-20
预期分子量:
358.5
产品形式:
A solution in methyl acetate
有效期:
730
纯度:
≥99% deuterated forms (d1-d4)
CAS号:
211105-40-7
分子式:
C20H30D4O5
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