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8-iso Prostaglandin F2α
品牌:Cayman
货号:16350-1 mg 规格:1 mg 目录价:¥2296
货号:16350-10 mg 规格:10 mg 目录价:¥17094
货号:16350-5 mg 规格:5 mg 目录价:¥9688
产品详情
产品名称:
8-iso Prostaglandin F2α
别名:
15-F2t-Isoprostane|8-epi PGF2α|8-iso-15(S)-Prostaglandin F2α|8-Isoprostane|iPF2α-III
产品描述:
8-iso PGF2α is an isoprostane produced by the non-enzymatic peroxidation of arachidonic acid in membrane phospholipids.{320,371,855} It is present in human plasma in two distinct forms - esterified in phospholipids and as the free acid. The ratio of these two forms is approximately 2:1, with a total plasma 8-iso PGF2α level of about 150 pg/ml in normal volunteers. In normal human urine, 8-iso PGF2α levels are about 180-200 pg/mg of creatinine.{320,371} 8-iso PGF2α is a weak TP receptor agonist in vascular smooth muscle.{6640} Conversely, 8-iso PGF2α inhibits platelet aggregation induced by U-46619 (10−6 M) and I-BOP (3 x 10−7 M) with IC50 values of 1.6 x 10−6 M and 1.8 x 10−6 M, respectively.{855}
保存温度:
-20
运输温度:
-20
预期分子量:
354.5
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
27415-26-5
分子式:
C20H34O5
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