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折扣/货期| 货号：100025 | 规格：1 ea (500 µl) | 目录价：￥4410 |
产品详情
产品名称:
5-OxoETE Receptor Polyclonal Antibody
别名:
GPR170|OXE Receptor|OXER1|Oxoeicosanoid Receptor 1|R527|TG1019
产品描述:
5-Oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OxoETE) is a potent stimulator of chemotaxis for eosinophils and neutrophils that mediates its action via a putative G-protein coupled receptor (GPCR).{10476,11003} The 5-OxoETE receptor couples to Gi/o to inhibit cyclic AMP production and to mobilize intracellular calcium.{10476,11003} Northern blot analysis reveals that the receptor is highly expressed on eosinophils and neutrophils, suggesting a key role in the inflammatory response.{11003} In addition, the protein can also be detected in tissues such as kidney and liver.{10476,11003} Cayman Chemical’s 5-OxoETE Receptor Polyclonal Antibody can be used in Western blot analysis (detection at 48 kDa) and immunocytochemistry. The high expression level of the receptor in leukocytes makes it the best positive control sample. When probing other tissue samples such as liver and kidney, membrane preparations or higher sensitivity detection systems may be required for visualization on immunoblot.
宿主来源:
Rabbit
实验应用:
ICC, WB
免疫原:
Synthetic peptide from the C-terminal region of human 5-OxoETE receptor
保存温度:
-20
运输温度:
-20
产品形式:
500 µl of Peptide affinity-purified polyclonal antibody.
有效期:
1095
来源:
Animal/Rabbit
促销活动
