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5-Bromo-2'-deoxycytidine

品牌：Cayman

官网链接

说明书

折扣/货期

货号：40644-1 g	规格：1 g	目录价：￥770
货号：40644-500 mg	规格：500 mg	目录价：￥406

产品详情

产品名称:

5-Bromo-2'-deoxycytidine

别名:

5-Bromodeoxycytidine|BrdC|BrdCyd|NSC 61765

产品描述:

5-Bromo-2'-deoxycytidine (BrdC) is a brominated derivative of the deoxyribonucleoside 2’-deoxycytidine (Item No. 34708).{67704} It induces DNA cross-linking and the formation of DNA strand breaks when incorporated into a DNA fragment in place of cytosine and exposed to UVB damage.{67705} BrdC inhibits cytopathogenicity induced by herpes simplex virus 1 (HSV-1) and HSV-2 in infected primary rabbit kidney (PRK) cells (MICs = 0.2-0.3 µg/ml).{36599} It decreases survival of U-1 melanoma cells and AG1522 non-cancerous cells and induces sensitization of both to radiation.{67704} BrdC also sensitizes tumors to radiation and reduces tumor volume in a mouse model of glioma using RT-2 cells infused with an adenovirus expressing HSV thymidine kinase (ADV-TK) after implantation.{67706} In vivo, BrdC is converted to 5-bromo-2'-deoxyuridine (BrdU; Item No. 15580) and has been used to label cardiac progenitor cells (CPCs) in a rat model of myocardial infarction.{67707}

保存温度:

-20

运输温度:

-20

预期分子量:

306.1

产品形式:

A solid

有效期:

1460

纯度:

≥95%