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2',3'-Dideoxycytidine-5'-O-triphosphate (sodium salt)
品牌:Cayman
货号:38374 规格:2.3 mg 目录价:¥2282
产品详情
产品名称:
2',3'-Dideoxycytidine-5'-O-triphosphate (sodium salt)
别名:
ddCTP|Dideoxycytidine 5'-triphosphate|Zalcitabine 5’-triphosphate
产品描述:
2',3'-Dideoxycytidine-5'-O-triphosphate is an active metabolite of the reverse transcriptase inhibitor zalcitabine (Item No. 16019).{61905} It is an inhibitor of DNA polymerases β and γ (Kis = 1.32 and 0.034 µM, respectively, for the human enzymes).{66342} 2',3'-Dideoxycytidine-5'-O-triphosphate (1 mM) inhibits HIV-1 replication in isolated human erythrocytes.{66343} Intraperitoneal administration of 2',3'-dideoxycytidine-5'-O-triphosphate-loaded erythrocytes reduces spleen and lymph node weight, limits increases in IgG levels, and decreases mediastinal lymph node swelling in a mouse model of LP-BM5 leukemic retrovirus infection-induced immunodeficiency.{66343}
保存温度:
-80
运输温度:
-80
预期分子量:
539.1
产品形式:
A solution in water
有效期:
730
纯度:
≥95%
分子式:
C9H12N3O12P3 • 4Na
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