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折扣/货期| 货号：10004454 | 规格：1 ea (500 µl) | 目录价：￥4410 |
产品详情
产品名称:
15-Lipoxygenase-2 Polyclonal Antibody
别名:
15-LO-2|15-LOX-2|ALOX15B|Arachidonate 15-Lipoxygenase Type II|Arachidonate 15-lipoxygenase B|Linoleate 13-lipoxygenase 15-Lob
产品描述:
Two types of 15-LO have been discovered and characterized, both of which metabolize arachidonic acid (AA) to produce 15(S)-hydroxyeicosatetraenoic acid (15(S)-HETE). 15-LO-1 oxygenates AA at both C15 and C12,{11792} whereas 15-LO-2 exclusively oxygenates C15 of AA.{4675} Human 15-LO-2 has a molecular mass of approximately 76 kDa and exhibits approximately 40% identity to the reticulocyte 15-LO-1.{4675,11789} Expression of 15-LO-2 appears to be restricted to prostate, lung, skin, and cornea and may play a role in the normal development of these tissues.{11790} The protein levels and enzymatic activity of 15-LO-2 are both down-regulated in prostate cancer compared with normal and benign prostate tissues, implicating a possible protective role for 15-LO-2 against tumor formation.{11790,8774,9075} Cayman Chemical’s 15-LO-2 polyclonal antibody can be used for western blot analysis for 15-LO-2 on samples of human origin. Other applications for use of this antibody have not yet been tested.
宿主来源:
Rabbit
实验应用:
ICC, IHC, WB
免疫原:
Synthetic peptide from the internal region of human 15-lipoxygenase-2
保存温度:
-20
运输温度:
-20
产品形式:
500 µl of peptide affinity-purified polyclonal antibody
有效期:
1095
来源:
Animal/Rabbit
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