货号:10004303 | 规格:1 ea (500 µl) | 目录价:¥4410 |
产品详情
产品名称:
11β-Hydroxysteroid Dehydrogenase (Type 1) Polyclonal Antibody
别名:
11-DH|11β-HSD1|Corticosteroid 11β-Dehydrogenase Isozyme 1|Short Chain Dehydrogenase/Reductase Family 26C Member 1
产品描述:
11β-Hydroxysteroid dehydrogenase (Type 1) (11β-HSD1) catalyzes the conversion of inactive cortisone to active cortisol in adipose tissue. mRNA and protein for this enzyme have been detected in a wide range of tissues including liver, kidney, testis, lung, heart, and colon.{12000} The enzyme’s expression is developmentally regulated, suggesting its importance in regulation of glucocorticoid action during embryonic development.{11999} Over-expression of 11β-HSD1 results in visceral obesity and metabolic syndrome including insulin-resistant diabetes, hyperlipidemia, and hyperphagia.{9545} Cayman’s 11β-HSD1 Polyclonal Antibody detects a 32 kDa protein in human, mouse, and rat liver samples by western blot analysis. The antibody can be used on paraffin-embedded tissue sections to detect 11β-HSD1 expression.
宿主来源:
Rabbit
实验应用:
IHC, WB
免疫原:
Synthetic peptide from the an internal region of human 11β-HSD1
保存温度:
-20
运输温度:
-20
产品形式:
500 µl of peptide affinity-purified polyclonal antibody
有效期:
1095
纯度:
≥98%
来源:
Animal/Rabbit
促销活动