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    11β-Hydroxysteroid Dehydrogenase (Type 1) Polyclonal Antibody
    品牌:Cayman
    货号:10004303 规格:1 ea (500 µl) 目录价:¥4410
    产品详情
    产品名称:
    11β-Hydroxysteroid Dehydrogenase (Type 1) Polyclonal Antibody
    别名:
    11-DH|11β-HSD1|Corticosteroid 11β-Dehydrogenase Isozyme 1|Short Chain Dehydrogenase/Reductase Family 26C Member 1
    产品描述:
    11β-Hydroxysteroid dehydrogenase (Type 1) (11β-HSD1) catalyzes the conversion of inactive cortisone to active cortisol in adipose tissue. mRNA and protein for this enzyme have been detected in a wide range of tissues including liver, kidney, testis, lung, heart, and colon.{12000} The enzyme’s expression is developmentally regulated, suggesting its importance in regulation of glucocorticoid action during embryonic development.{11999} Over-expression of 11β-HSD1 results in visceral obesity and metabolic syndrome including insulin-resistant diabetes, hyperlipidemia, and hyperphagia.{9545} Cayman’s 11β-HSD1 Polyclonal Antibody detects a 32 kDa protein in human, mouse, and rat liver samples by western blot analysis. The antibody can be used on paraffin-embedded tissue sections to detect 11β-HSD1 expression.
    宿主来源:
    Rabbit
    实验应用:
    IHC, WB
    免疫原:
    Synthetic peptide from the an internal region of human 11β-HSD1
    保存温度:
    -20
    运输温度:
    -20
    产品形式:
    500 µl of peptide affinity-purified polyclonal antibody
    有效期:
    1095
    纯度:
    ≥98%
    来源:
    Animal/Rabbit
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