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折扣/货期| 货号：10008989-100 µg | 规格：100 µg | 目录价：￥2212 |
| 货号：10008989-50 µg | 规格：50 µg | 目录价：￥1190 |
| 货号：10008989-500 µg | 规格：500 µg | 目录价：￥5236 |
产品详情
产品名称:
11β-Prostaglandin F2α-d4
别名:
11-epi PGF2α-d4|11β-PGF2α-d4|9α,11β-PGF2α-d4
产品描述:
11β-Prostaglandin F2α-d4 (11β-PGF2α-d4) is intended for use as an internal standard for the quantification of 11β-PGF2α (Item No. 16520) by GC- or LC-MS. 11β-PGF2α is the primary metabolite of PGD2 (Item No. 12010).{57057} It is formed from PGD2 via the NADPH-dependent aldo-keto reductase PGF synthase (PGFS; Item No. 10007940) in the liver or lung.{57058} 11β-PGF2α induces contraction of isolated cat iris sphincter, which endogenously expresses high levels of PGF2α (FP) receptors, with an EC50 value of 0.045 µM.{57057} It also induces contraction of isolated human bronchial smooth muscle when used at concentrations ranging from 0.1 to 30 µM.{1756} 11β-PGF2α (0.1 and 1 µM) induces phosphorylation of ERK and CREB, as well as increases the viability of MCF-7 breast cancer cells stably expressing the FP receptor when used at concentrations of 0.1 and 1 µM.{57059}
保存温度:
-20
运输温度:
-20
预期分子量:
358.5
产品形式:
A solution in ethanol
有效期:
365
纯度:
≥99% deuterated forms (d1-d4)
CAS号:
1240398-18-8
分子式:
C20H30D4O5
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